Research: Mycoplasma genitalium antimicrobial resistance surveillance (MARS)

Imported from official source

Surveillance of antimicrobial resistance in Mycoplasma genitalium (M. genitalium) in England is conducted through the M. genitalium Antimicrobial Resistance Surveillance (MARS) Programme. MARS sentinel surveillance data is obtained annually from a network of sexual health services and their associated laboratories. The programme aims to:

  • estimate the prevalence of macrolide and fluoroquinolone resistance in M. genitalium infections in individuals attending sentinel sexual health services in England
  • determine the demographic, behavioural and clinical factors associated with resistance
  • Surveillance of antimicrobial resistance is critical in guiding national management guidelines to ensure appropriate treatments. Continued surveillance of antimicrobial resistance in M. genitalium  through MARS will provide a rich resource for informing future updates to management guidelines in the UK.

    Pilot collections for this programme were conducted in 2019 and 2020. Previous MARS reports are available from the UK Government Web Archive. 

    Cases of treatment failure to second-line therapeutics, such as moxifloxacin, should be reported to UK Health Security Agency using the HIV and STI Data Exchange

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    September 21, 2026 09:30
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